In pregnancy, a 2013 review noted that "nicotine is only 1 of more than 4000 compounds to which the fetus is exposed through maternal smoking. Of these, ∼30 compounds have been associated with adverse health outcomes. Although the exact mechanisms by which nicotine produces adverse fetal effects are unknown, it is likely that hypoxia, undernourishment of the fetus, and direct vasoconstrictor effects on the placental and umbilical vessels all play a role. Nicotine also has been shown to have significant deleterious effects on brain development, including alterations in brain metabolism and neurotransmitter systems and abnormal brain development." It also notes that "abnormalities of newborn neurobehavior, including impaired orientation and autonomic regulation and abnormalities of muscle tone, have been identified in a number of prenatal nicotine exposure studies" and that there is weak data associating fetal nicotine exposure with newborn facial clefts , and that there is no good evidence for newborns suffering nicotine withdrawal from fetal exposure to nicotine. 
Within 30 minutes of ingestion of gliadin, for those with antigliadin antibodies, there will be an inflammatory response. This inflammatory response can provide many symptoms, including some that mimic attention deficit disorder. We all know that some kids are labeled as having ADHD because of their abnormal behavior seen within 30 minutes of eating a cupcake. It is not the sugar in the icing, it is the gluten in the cake. Antigliadin antibodies are found in over 58% of children with biotoxin-associated illness.